Clinical Trials & Research

Coronavirus disease 2019 (COVID-19) disproportionately affects patients 65 years and older. Age-related impaired host immunity has been implicated for severe outcomes of COVID-19. Researchers have performed a study on large data set to understand better the molecular basis of vulnerability in aged COVID-19 patients. They observed certain age-linked immunoinflammatory factors associated with severe COVID-19 and
0 Comments
A distinguishing feature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to severe acute respiratory syndrome (SARS) is that it is spread not only via symptomatic people but also asymptomatic and pre-symptomatic people. Asymptomatic cases are becoming of increasing concern due to the potential of people unknowingly causing local outbreaks within their communities. In
0 Comments
Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system attacks the body’s own tissues, causing widespread inflammation and damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. Asian SLE patients suffer from more severe disease and damage compared to patients in western countries.
0 Comments
Researchers worldwide hypothesized that the development of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help to reduce transmission and help to lower the mortality rate. The vaccines developed against coronavirus disease 2019 (COVID-19) had to undergo several clinical trials before they could be considered safe for human use. Patients of various age
0 Comments
Scientists have recently tried to explain the factors that could be responsible for the recent outbreaks of coronavirus disease 2019 (COVID-19) in Israel. Their observations reveal that the prevalence of the more infectious delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and waning vaccine efficacy results in the outbreaks. As preventive interventions, they
0 Comments
The ongoing coronavirus disease 2019 (COVID-19) pandemic has caused an economic and healthcare crisis. COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive-stranded and RNA virus belonging to the family Coronaviridae. This virus is highly virulent and has already claimed more than 4.66 million live worldwide. Study: Neutralizing Monoclonal Antibodies
0 Comments
In a report currently available on the bioRxiv* preprint server, scientists from the USA have demonstrated that immunity induced by mRNA-based coronavirus disease 2019 (COVID-19) vaccines in previously severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected people has the highest robustness and durability with cross-reactivity against different viral variants. Study: Differential antibody dynamics to SARS-CoV-2 infection
0 Comments
Cholesterol manufactured in the brain appears to play a key role in the development of Alzheimer’s disease, new research indicates. Scientists from the University of Virginia School of Medicine and their collaborators found that cholesterol produced by cells called astrocytes is required for controlling the production of amyloid beta, a sticky protein that builds up
0 Comments
Heat exposure can effectively inactive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), similar to other viruses. Common touchpoints in private and public vehicles can receive heat treatment as a form of sanitization to kill heat-sensitive viruses, such as SARS-CoV-2. This form of sanitization can be performed routinely
0 Comments
A new study by the ICTA-UAB establishes that the population density of hunter-gatherer groups was reduced where they depended heavily on meat to survive. Hunter-gatherer populations with a strong seasonal dependence on meat in their diets had fewer people per square kilometer than those that had abundant plant foods throughout the year. This new result
0 Comments
Sandrine V. Pierre, Ph.D., associate professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine and interim director of the Marshall Institute for Interdisciplinary Research (MIIR), has been awarded a Research Project Grant (R01), one of the most competitive grants issued by the National Institutes of Health (NIH). Pierre was awarded
0 Comments
A school-based survey conducted by scientists of the University of Zurich has revealed that about 60% of primary and secondary school students in Zurich, Switzerland, perceive mask-wearing at school as a useful intervention for controlling severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. However, some students have reported discomfort and side effects. The detailed report
0 Comments
GAITHERSBURG, Md., Sept. 8, 2021 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX), a biotechnology company dedicated to developing and commercializing next-generation vaccines for serious infectious diseases, today announced enrollment of the first participants in a Phase 1/2 study to evaluate the safety and immunogenicity of a combination vaccine using Novavax’ seasonal influenza and COVID-19 vaccines. The
0 Comments
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the virus that causes coronavirus disease 2019 (COVID-19) – is not associated with neuroaxonal damage, according to a new study from researchers in Germany. Neurological symptoms have been observed in about one-third of coronavirus cases. However, the full extent of the virus’s impact on the brain
0 Comments
LA ROCHELLE, France. Sept 6, 2021 – Valbiotis, a French research and development company committed to scientific innovation for preventing and combating metabolic diseases, announces that it has completed the recruitment of 120 volunteers for the Phase II HEART clinical study at the beginning of September 2021, in accordance with the schedule announced by the
0 Comments
Since it was first detected in December 2019 in Wuhan, China, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the virus that causes coronavirus disease 2019 (COVID-19) – has infected over 217 million people worldwide. To date, this has led to over 4.56 million deaths worldwide. The COVID-19 pandemic continues to affect more
0 Comments
SAN FRANCISCO, Sept. 3, 2021.  Quantum Leap Healthcare Collaborative, the sponsor of the I-SPY COVID Trial, today announced that the Famotidine Celecoxib arm has been dropped from the trial due to futility, based on the low likelihood of success. The Famotidine Celecoxib combination was chosen for testing because of their anti-histamine and anti-inflammatory mechanism of
0 Comments
Don and Karen Cohn have given $2.5 million to create the Don and Karen Cohn Chancellor’s Endowed Chair in Neurosurgery at University of California San Diego School of Medicine. The gift will support excellence in research, education and clinical care in the field of neurological surgery. Alexander Khalessi, MD, neurosurgeon at UC San Diego Health,
0 Comments
MANHASSET, N.Y., Sept. 2, 2021. As part of a new National Institutes of Health (NIH) coronavirus disease 2019 (COVID-19) vaccine clinical trial, The Feinstein Institutes for Medical Research – the science arm of Northwell Health – delivered its first set of extra shots to eligible New York patients with an autoimmune disease. An estimated 8
0 Comments
Ziath, a leading supplier of equipment, software and consumables to simplify your sample management process, offers a range of CryzoTraq™ tubes designed for high integrity cryogenic storage of biological specimens at temperatures down to -196°C. Image Credit: Ziath Ltd Related Stories CryzoTraq™ 2D barcoded tubes are manufactured in a Class 7 cleanroom using medical-grade polypropylene. 
0 Comments
MADRID, Aug. 31, 2021. Results from a new human clinical study demonstrate a significant capacity for Pharmactive’s potent all-natural affron standardized saffron extract to promote restorative sleep. The ingredient showed its effect in a single, low dose taken just one hour before bedtime, making affron a natural ingredient that is very easy to consume. Moreover,
0 Comments
ABBOTT PARK, Ill., Aug. 27, 2021.  Abbott today announced results of the landmark GUIDE-HF clinical trial, a 1,000 patient randomized study designed to assess the benefits of the CardioMEMS HF System in people living with NYHA Class II, III and IV heart failure. Data adjusted for the impact of COVID-19 show a strong reduction in
0 Comments
Until now, patients with heart failure with preserved ejection fraction – the most common type of heart failure in the elderly – have had no access to evidenced-based treatments. For the first time, a large clinical trial led by Prof. Dr. Stefan Anker from Charité – Universitätsmedizin Berlin has identified a drug which has a
0 Comments
CINCINNATI, Aug. 26, 2021.  Airway Therapeutics, Inc. (Airway), a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory and inflammatory diseases, announced dosing of the first patient on August 17, 2021 in the AT-100 (rhSP-D) Phase 1b trial in mechanically-ventilated COVID-19 patients. The clinical
0 Comments
As the election to recall California Gov. Gavin Newsom approaches, abortion-rights groups are warning that Californians’ right to an abortion is on the ballot. Newsom, a Democrat, himself tweeted that “abortion access” is at stake. “There’s no question that if a Republican is elected, access to abortion in California will be restricted,” Jodi Hicks, president
0 Comments
NEW YORK, Aug. 24, 2021. Oramed Pharmaceuticals Inc., a clinical-stage pharmaceutical company focused on the development of oral drug delivery platforms, announced today that it has enrolled and randomized over 25% of the planned 450 patients for its Phase 3 ORA-D-013-2 trial of its oral insulin capsule ORMD-0801 for the treatment of type 2 diabetes
0 Comments