Allergies & Asthma

Among children with uncontrolled, moderate-to-severe asthma, treatment with the biologic dupilumab (Dupixent) was associated with a reduction in exacerbation and improvements in lung function in phase III findings from the international VOYAGE trial. Evidence of lung function improvement occurred within 2 weeks of treatment initiation, and was sustained during the 52-week randomized, placebo-controlled trial. Compared
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A first-in-class drug under development for severe asthma passed what its developers hope is the final test: achieving its primary endpoint in a phase III registration trial dubbed NAVIGATOR and now reported in a major journal. Tezepelumab, a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), cut the annualized rate of asthma exacerbations by more than
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A novel gene therapy for severe combined immunodeficiency from adenosine deaminase deficiency (ADA-SCID) restored immune cell counts without death or need for enzyme replacement therapy, researchers reported. Survival without needing to re-initiate pegylated ADA enzyme replacement therapy, or have a rescue allogeneic hematopoietic stem cell transplantation (AHCT), was 95% to 97% at last follow-up at
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Rather than site-wide food bans or allergen-restricted zones, allergy training, action plans, and available epinephrine to treat suspected anaphylaxis are recommended to address allergic reactions to food at child care centers and schools, according to new practice guidelines. Not only has research found little evidence that food bans work, such restrictions can pose monitoring and
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Contents of baby’s first stool were a biomarker for early-life allergy risk in a study of 100 infants. Infants who developed IgE-mediated atopy by age 1 showed a significantly poorer environment in their meconium — the fecal matter accumulated prior to birth and typically expelled within a few days of delivery — for microbiotal development
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One of the most talked about food allergies is peanut. Though not the most common food allergy, it’s the most common food associated with severe allergic reactions – so it’s an important one to be educated on. Consider this overview on peanut allergy: from symptoms, diagnosis, and avoiding peanuts, to options for treating the cause.
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As the world starts to emerge from the COVID-19 crisis, another global — and even more devastating — existential threat persists: climate change. Worldwide, climate-driven disasters including storms, droughts, fires, and floods displaced more than 10 million people since last September. Here in the western U.S., we face increasingly catastrophic wildfire seasons with powerful effects
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A graded dosing protocol allowed two patients with hypersensitivity reactions to the first dose of Moderna’s COVID-19 vaccine to receive their second doses safely, researchers said. The patients — one with an immediate hypersensitivity reaction managed on site and one needing emergency department transport — got divided second doses, reported S. Shahzad Mustafa, MD, of
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March is National Nutrition Month — which highlights important topics for everyone. Adequate nutrition is critical to all, but for those with limited diets due to food allergy, it can be more of a challenge to meet. There are also so many different layers to staying safe that need to be considered when it comes
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Asthma patients with confirmed COVID-19 were no more likely to require hospitalization or mechanical ventilation than patients without asthma, researchers found. Moreover, the asthma patients were less likely to die from COVID, reported Lacey Robinson, MD, of Massachusetts General Hospital in Boston, at the virtual annual meeting of the American Academy of Allergy, Asthma &
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Managing your allergies is a big job – and can be a lifesaving practice. Like anything these days, there’s technology that can help make it simpler. In this blog, we’re talking about free apps that can help with adherence to your allergy treatment and medications, as well as food and environmental allergy management. Adherence apps
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